Get my FREE PCOS 1. Guide to Health and Hope. De- Mystifying Myo- Inositol. Join Tarryn as she helps women improve their PCOS Diet to overcome the symptoms and impact of Polycystic Ovarian Syndrome. Are you one of the 30% of women suffering from PCOS?Click a link below to learn more about a specific symptom and what you can do about it. If you have PCOS, which affects between 4 and 12 percent. How injectables are used as infertility treatment for PCOS and ovulation problems. Injectable gonadotropins, FSH – after Clomid fails for polycystic ovarian syndrome. Do you have PCOS (polycystic ovary syndrome)? Taking metformin but it makes you feel ill? Discover which natural therapies could be just as effective, but without the. July 2. 2, 2. 01. By Amy Medling, founder of PCOS Diva. Lately, myo- inositol seems to be the other “m”- word in the PCOS world (the first being metformin). I do want to state up front that this is not a miracle pill. Let’s take a closer look. Myo- inositol is one of nine different types of inositol and can be found naturally in many foods such as fruits, nuts and beans. It is a precursor to a number of “signaling molecules” that essentially tell cells how to behave. Metformin for PCOS & Pregnancy. This page has a simple goal -- to provide journal abstracts regarding metformin use for infertility, specifically PCOS, and abstracts.Of the nine different types of inositol, two have insulin- sensitizing capabilities: myo- inositol and d- chiro- inositol (My focus for this article is going to be on myo- inositol.) Myo- inositol is integral to properly functioning insulin- receptors and has also been linked to the activation of serotonin (a “feel good” hormone) receptors, which could relieve depression and improve appetite, mood and anxiety (1, 2). PCOS has been linked to a deficiency in myo- inositol. Supplying extra myo- inositol appears to temporarily correct the malfunctioning insulin pathways and reduce the signs and symptoms of insulin resistance. The researchers concluded, “MYO . Myo- inositol and folic acid were given daily as INOFOLIC. Those treated had at least one menstrual cycle, and of these, seventy two percent continued ovulating normally. Forty percent of the women became pregnant and the study concluded that, “Myo- inositol is a simple and safe treatment that is capable of restoring spontaneous ovarian activity and consequently fertility in most patients with PCOS. This therapy did not cause multiple pregnancy.”Helps with weight loss and appetite control. A randomized double- blind trial which is the gold standard of research, gave 9. Researchers discovered that ovulation significantly increased, as did the frequency of normal progesterone values in the luteal phase and estradiol levels in the myo- inositol group. This study noted less metabolic benefits to those women who were overweight, but also that the myo- inositol group lost a significant amount of weight and had lowered leptin (an appetite regulating hormone) levels. The researchers concluded that, “These data support a beneficial effect of myo- inositol in women with oligomenorrhea and polycystic ovaries in improving ovarian function.”Improves egg quality. Another study showed that high levels of myo- inositol within follicles may be a marker for good follicular development and good oocyte or egg quality. The researchers stated, “We propose that higher concentrations of MI (Myo- inositol) and E2 (estradiol) in human FF (follicular fluid) appear to play a role in follicular maturity and provide a marker of good quality oocytes. In conclusion, follicles containing good quality oocytes have higher concentrations of MI (Myo- inositol) in FF (follicular fluid)”Another study published last April measured the effects of both myo- inositol and d- chiro- inositol in women undergoing fertility treatments. The results showed that women who received myo- inositol had better quality and more mature eggs. They also had more pregnancies than those who took d- chiro- inositol. Ask your doctor about supplementing with myo- inositol. This is your health and if you like what you just read, then talk to your doctor about taking myo- inositol. Chances are your doctor may have never even heard of myo- inositol as a therapy for PCOS. My advice is to be, “A Diva at the Doctor.” Advocate for yourself. Ask for their support. Sources: 1.“Biochemistry”; Molecular level interaction of the human acidic fibroblast growth factor with the antiangiogenic agent, inositol hexaphosphate; Kumar SM, et al; 2. Metabolic Brain Diseases”; Effects of myo- inositol versus fluoxetine and imipramine pretreatments on serotonin 5. HT2. A and muscarinic acetylcholine receptors in human neuroblastoma cells; Brink CB, et al; 2.
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November 2017
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